ABSTRACT

We present exact conditions for stability of monomorphic equilibria in a general multilocus multiallele system and of specific polymorphic equilibria in general one- and two-locus multiallele systems. We show how these exact results on one- and two-locus systems can be used in approximate analysis of polymorphic equilibria in multilocus systems under selection strong relative to recombination. We determine conditions for existence and stability of polymorphic equilibria in specific models of quadratic stabilizing selection on additive polygenic traits.